- Original Article
- Cardiology
- Importance of pulmonary valve morphology for pulmonary valve preservation in tetralogy of Fallot surgery: comparison of the echocardiographic parameters
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Su Jin Choi, Jung Eun Kwon, Da Eun Roh, Myung Chul Hyun, Hanna Jung, Young Ok Lee, Joon Yong Cho, Yeo Hyang Kim
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Clin Exp Pediatr. 2020;63(5):189-194. Published online November 8, 2019
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Question: Is echocardiographic examination is useful for surgical method decision in patients with tetralogy of Fallot (TOF)?
Finding: Various echocardiographic parameters serve as predictors for determining surgical methods for TOF patients. However, the PV morphology and tissue characteristics should also be considered.
Meaning: A full dependence on the size of the pulmonary valve annulus (PVA), the z score, and the ratio of the size of PVA to aortic valve annulus or descending aorta surgery may result in inadequate surgical results during TOF total correction. |
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- Nephrology (Genitourinary)
- Variation in clinical usefulness of biomarkers of acute kidney injury in young children undergoing cardiac surgery
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Hee Sun Baek, Youngok Lee, Hea Min Jang, Joonyong Cho, Myung Chul Hyun, Yeo Hyang Kim, Su-Kyeong Hwang, Min Hyun Cho
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Clin Exp Pediatr. 2020;63(4):151-156. Published online February 5, 2020
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Question: Can clinical usefulness of biomarkers of acute kidney injury vary on the clinical circumstances?
Finding: In young children undergoing cardiac surgery, urine KIM-1/Cr level peaked at 24 hours with significant difference from baseline level and was significantly higher at 6 hours in the AKI group. However, urine NGAL/Cr and IL-18/Cr levels showed no specific trend with time for 48 hours after cardiac surgery.
Meaning: Urine KIM-1/Cr concentration could be considered a good biomarker for early AKI prediction after open cardiac surgery in young children. |
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- Cardiology
- Radiofrequency catheter ablation of atrioventricular nodal reentry tachycardia in children and adolescents: a single center experience
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Myung Chul Hyun
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Clin Exp Pediatr. 2017;60(12):390-394. Published online December 22, 2017
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Purpose Atrioventricular nodal reentry tachycardia (AVNRT) is less common in pediatric patients than in adult patients. Thus, data for pediatric AVNRT patients are insufficient. Hence, we aimed to analyze the patient characteristics, treatment, and any recurrences in pediatric AVNRT patients. MethodsWe reviewed the records of 50 pediatric AVNRT patients who had undergone radiofrequency catheter ablation (RFCA) between January 1998 and December 2016... |
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- Comparison between Kawasaki disease with lymph-node-first presentation and Kawasaki disease without cervical lymphadenopathy
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Jung Ok Kim, Yeo Hyang Kim, Myung Chul Hyun
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Clin Exp Pediatr. 2016;59(2):54-58. Published online February 29, 2016
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Purpose We evaluated the characteristics of patients with Kawasaki disease (KD) who presented with only fever and cervical lymphadenopathy on admission, and compared them with the characteristics of those who presented with typical features but no cervical lymphadenopathy. MethodsWe enrolled 98 patients diagnosed with KD. Thirteen patients had only fever and cervical lymphadenopathy on the day of admission (group 1), 31 had... |
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- Sensorineural hearing loss in patients with Kawasaki disease
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Sun Young Park, Young Hyun Kim, Yeo Hyang Kim, Myung Chul Hyun, Young Hwan Lee
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Clin Exp Pediatr. 2015;58(11):434-439. Published online November 22, 2015
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Purpose Kawasaki disease involves acute febrile systemic vasculitis that can cause a variety of symptoms by affecting various organs. Here, we aimed to evaluate the prevalence, causes, and prognosis of sensorineural hearing loss (SNHL) occurring in children with Kawasaki disease. MethodsPatients who were diagnosed with Kawasaki disease and received inpatient treatment in the Pediatrics Department at one of three university hospitals in... |
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- Outcome of inflammatory response after normothermia during cardiopulmonary bypass surgery in infants with isolated ventricular septal defect
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Dong Sub Kim, Sang In Lee, Sang Bum Lee, Myung Chul Hyun, Joon Yong Cho, Young Ok Lee
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Clin Exp Pediatr. 2014;57(5):222-225. Published online May 31, 2014
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Purpose A recent study analyzing several cytokines reported that long cardiopulmonary bypass (CPB) time and long aortic cross clamp (ACC) time were accompanied by enhanced postoperative inflammation, which contrasted with the modest influence of the degree of hypothermia. In this present study, we aimed to examine the effect of CPB temperature on the clinical outcome in infants undergoing repair of isolated... |
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- Predictors of nonresponse to intravenous immunoglobulin therapy in Kawasaki disease
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Hyo Min Park, Dong Won Lee, Myung Chul Hyun, Sang Bum Lee
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Clin Exp Pediatr. 2013;56(2):75-79. Published online February 25, 2013
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Purpose It has been reported that 10% to 20% of children with Kawasaki disease (KD) will not respond to intravenous immunoglobulin (IVIG) treatment. In this study, we aimed to identify useful predictors of therapeutic failure in children with KD. MethodsWe examined 309 children diagnosed with KD at the Kyungpook National University Hospital and the Inje University Busan Paik Hospital between January 2005... |
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- Clinical features and surgical outcomes of complete transposition of the great arteries
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Suk Jin Hong, Hee Joung Choi, Yeo Hyang Kim, Myung Chul Hyun, Sang Bum Lee, Joon Yong Cho
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Clin Exp Pediatr. 2012;55(10):377-382. Published online October 29, 2012
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Purpose This single-center study aimed to assess the clinical features and surgical approaches and outcomes of complete transposition of the great arteries (TGA). MethodsTGA patients who had undergone surgical correction at the Kyungpook National University Hospital from January 2000 to December 2010, were retrospectively evaluated for patient characteristics, clinical manifestation, preoperative management, intraoperative findings, postoperative progress, and follow-up status. ResultsTwenty-eight patients (17 boys... |
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- Case Report
- Secondary renal amyloidosis in a 13-year-old girl with bronchiectasis
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Eun Ae Yang, Dong Won Lee, Myung Chul Hyun, Min Hyun Cho
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Clin Exp Pediatr. 2010;53(7):770-773. Published online July 31, 2010
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A 13-year-old girl was diagnosed with non-cystic fibrosis (CF)-related multifocal bronchiectasis accompanied by nephrotic-range proteinuria of unknown cause. On renal biopsy, there were many segmental homogeneous deposits of amyloid tissue with positive Congo red staining in the glomeruli and interstitium. On electron microscopy, relatively straight, non-branching, randomly arranged amyloid fibrils were showed in the mesangium of the glomeruli. These fibrils... |
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- Original Article
- NT-proBNP as a useful tool in diagnosing incomplete Kawasaki disease
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Dong Won Lee, Yeo Hyang Kim, Myung Chul Hyun, Tae Chan Kwon, Sang Bum Lee
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Clin Exp Pediatr. 2010;53(4):519-524. Published online April 15, 2010
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Purpose : To determine the efficacy of the N-terminal fragment of B-type natriuretic peptide (NT-proBNP) as a useful diagnostic method in children with incomplete Kawasaki disease (KD).
Methods : Ninety-six patients who were diagnosed as having KD between January 2008 and June 2009 were enrolled in the study. American Heart Association recommendations for diagnosis were used, and patients were divided into... |
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- Early postoperative arrhythmias after open heart surgery of pediatric congenital heart diseas
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Hee Joung Choi, Yeo Hyang Kim, Joon Yong Cho, Myung Chul Hyun, Sang Bum Lee, Kyu Tae Kim
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Clin Exp Pediatr. 2010;53(4):532-537. Published online April 15, 2010
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Purpose : Early postoperative arrhythmias are a major cause of mortality and morbidity after open heart surgery in the
pediatric population. We evaluated the incidence and risk factors of early postoperative arrhythmias after surgery of congenital
heart disease.
Methods : From January 2002 to December 2008, we retrospectively reviewed the medical records of the 561 patients who
underwent cardiac surgery in Kyungpook National University... |
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- Case Report
- Plastic bronchitis in children: 2 cases
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Yeo Hyang Kim, Hee Jung Choi, Jung Ok Kim, Myung Chul Hyun
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Clin Exp Pediatr. 2009;52(7):832-836. Published online July 15, 2009
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Plastic bronchitis is a rare disorder characterized by the formation of extensive, obstructing endobronchial casts. It is associated with asthma and complex cardiac defects such as those requiring the Fontan procedure. The treatment of plastic bronchitis comprises conventional therapy involving spontaneous expectoration and bronchoscopic removal and specific therapy with several new drugs. Herein, we describe the cases of 2 patients... |
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- The changes in signal-averaged electrocardiogram after surgical correction of congenital heart disease
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Yeo Hyang Kim, Hee Jung Choi, Gun Jik Kim, Joon Yong Cho, Myung Chul Hyun, Sang Bum Lee
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Clin Exp Pediatr. 2009;52(12):1364-1369. Published online December 15, 2009
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Purpose : To analyze abnormal ventricular activation in childhood congenital heart disease induced by postoperative changes in ventricular volume and pressure and ventricular scar formation using signal-averaged electrocardiography (SAECG).
Methods : Fifty-two patients who had undergone open heart surgery (OHS) were enrolled. Patients were divided into the following 3 groups: right ventricular volume overload (atrial septal defect, group1), left ventricular... |
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- Clinical features and results of recent neonatal cardiac surgery - A review of 82 cases in one hospital
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Ki Won Oh, Jung Ok Kim, Joon Yong Cho, Myung Chul Hyun, Sang Bum Lee
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Clin Exp Pediatr. 2007;50(7):665-671. Published online July 15, 2007
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Purpose : The purpose of this study was to investigate the clinical features and outcome in newborns undergoing cardiac surgery.
Methods : Eighty two neonates underwent heart surgery for congenital heart defect at Kyungpook National University Hospital between March 2000 and February 2006. Patient characteristics (sex, age, diagnosis), pre-operative conditions, operation type, postoperative complications and mortality were reviewed retrospectively.
Results : In... |
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- Clinical features and surgical results of ruptured sinus of valsalva aneurysm
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Tae Ho Lee, Dong Won Lee, Joon Yong Cho, Myung Chul Hyun, Sang Bum Lee
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Clin Exp Pediatr. 2006;49(3):287-291. Published online March 15, 2006
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Purpose : Aneurysms of sinus valsalva are rare anormalies thought to be primarily congenital in origin, progressing into death by acute heart failure in cases of rupture. Surgical correction is the only method of treatment. With these clinical implications, we reviewed the clinical characteristics and surgical results of patients with ruptured sinus of valsalva aneurysm.
Methods : Between January 1991... |
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- Usefulness of Intraoperative Transesophageal Echocardiography
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Dong Won Lee, Byung Mok Kim, Sei Young Kim, Yeo Hyang Kim, Myung Chul Hyun, Sang Bum Lee
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Clin Exp Pediatr. 2004;47(12):1281-1286. Published online December 15, 2004
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Purpose : This study was undertaken to learn the usefulness, cost-effectiveness and safety of intraoperative transesophageal echocardiography(ITEE) during open heart surgery for congenital heart diseases.
Methods : The usefulness and safety of ITEE were assessed in 254 patients who underwent open heart surgery for congenital heart diseases from January 1, 2001 to June 30, 2003, with retrospective chart reviews and a... |
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- Hypoxia Induced Expression of Vascular Endothelial Growth Factor in Rat Pulmonary Artery Smooth Muscle Cells
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Un Seok Nho, Yeo Hyang Kim, Myung Chul Hyun, Sang Bum Lee
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Clin Exp Pediatr. 2003;46(2):167-172. Published online February 15, 2003
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5% CO2-95% air atmosphere. The smooth muscle cells were confirmed by immunostaining with smooth muscle myosin and α-smooth muscle actin antibodies. The VEGF gene expression in the hypoxic group was compared with the one in control the group as well as the one in the starved group by RT-PCR and Northern blot hybridization.
Results : There was no statistically significant difference... |
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- Serial Changes of Cardiac Troponin I After
Pediatric Open Heart Surgery
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Yeo Hyang Kim, Myung Chul Hyun, Sang Bum Lee
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Clin Exp Pediatr. 2002;45(2):208-213. Published online February 15, 2002
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Purpose : The major cause of cardiac dysfunction, after open heart surgery for congenital heart disease, is perioperative myocardial injury. Cardiac troponin I is found only within the myocardial cell, so it can be used as a biochemical marker of the myocardial injury. We performed this study to evaluate the worth of cardiac troponin I as a biochemical marker reflecting... |
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- Clinical Features and ECG Findings of Supraventricular Tachycardia in Pediatric Patients
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Chang Hwan Jang, Myung Chul Hyun
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Clin Exp Pediatr. 2001;44(9):1012-1018. Published online September 15, 2001
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Purpose : Supraventricular tachycardia(SVT) is the most frequent symptomatic arrhythmia in
children. We performed this study to disover the SVT mechanisms, age at SVT onset, symptoms
and ECG findings of SVT and effect of adenosine on SVT.
Methods : We studied 57 patients(male : 30, female : 27, age : 1 day-15.8 years) who had been admitted
or transferred due to SVT from January,... |
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- M-mode Echocardiographic Abnormalities in
Infants of Diabetic Mothers
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Myung Chul Hyun
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Clin Exp Pediatr. 2001;44(8):881-885. Published online August 15, 2001
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Purpose : The purpose of this study was to evaluate M-mode echocardiographic abnormalities in infants of relatively well controlled diabetic mothers and to determine the timing of spontaneous regression.
Methods : Echocardiographic study was prospectively carried out in 9 neonates born to diabetic mothers(infants of diabetic mothers, IDM) and 6 newborn infants(control) matched for weight and age. And the study were... |
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- Serial Changes of CK, CK-MB after Radiofrequency Catheter
Ablation in Pediatric Patients
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Se Young Kim, Myung Chul Hyun
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Clin Exp Pediatr. 2001;44(8):893-898. Published online August 15, 2001
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Purpose : To investigate the degree of myocardial injury incurred by radiofrequency catheter ablation(RFCA), we serially measured CK, CK-MB levels in 24 pediatric paroxysmal supraventricular tachycardia patients undergoing RFCA(male : 12, female : 12, mean age : 10.5 years, mean weight : 37.2 kg).
Methods : We serially measured blood CK, CK-MB levels, 1 day before RFCA(baseline), 8 hours after... |
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- The Effectiveness of Propofol on Pediatric Cardiac
Catheterization and Electrophysiologic Study
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Woo Saeng Park, Myung Chul Hyun
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Clin Exp Pediatr. 2001;44(7):773-777. Published online July 15, 2001
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Purpose : Our purpose was to evaluate the effectiveness of propofol on pediatric cardiac catheterization or radiofrequency catheter ablation.
Methods : We measured the serial changes of arterial oxygen saturation, heart rate, systolic and diastolic blood pressure at 4 stages, a baseline(during normal sleep), stage 1(just after loading of propofol 2 mg/kg over 10 minutes), stage 2(10-15 minutes after propofol continuous... |
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- Electrophysiologic Study of Cardiac
Conduction System in Children
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Chae Ok Shin, Myung Chul Hyun
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Clin Exp Pediatr. 2001;44(10):1135-1140. Published online October 15, 2001
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Purpose : Pediatric cardiac arrhythmias are increasing but there is no normal values of cardiac electrophysiologic studies(EPS) in Korean children. So we performed cardiac EPS in children undergoing cardiac catheterization for mild congenital heart disease without cyanosis and ECG abnormality.
Methods : We studied 24 children(male : 9, female : 15) with mild congenital heart disease(PDA : 10, VSD : 8,... |
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- Morphometric Analysis of the Infundibulum in Tetralogy of Fallot
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Su Hee Kwak, Myung Chul Hyun, Sang Bum Lee
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Clin Exp Pediatr. 2000;43(9):1187-1191. Published online September 15, 2000
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Purpose : The morphogenic mechanism of tetralogy of Fallot is known to be an antero-superior deviation and hypertrophy of the subpulmonary infundibulum. We performed this study to measure the subpulmonary infundibulum in patients with tetralogy of Fallot and compare those with normal control.
Methods : Echocardiographic data and medical reports of 12 patients, with classical tetralogy of Fallot who were diagnosed... |
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- Transcatheter Closure of the Patent Ductus Arteriosus
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Young A Lee, Myung Chul Hyun, Sang Bum Lee
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Clin Exp Pediatr. 2000;43(9):1200-1206. Published online September 15, 2000
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Purpose : Transcatheter closure of the patent ductus arteriosus(PDA) is a well-established, effective therapeutic modality, and many kinds of devices have been used to perform this closure. The aim of this study is to compare the effects of different kinds of devices.
Methods : We reviewed retrospectively the charts of 43 patients who were admitted to Kyungpook University Hospital between June... |
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- Short-term Result of Radiofrequency Catheter Ablation in
Pediatric Patients with Paroxysmal Tachycardia
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Hee Suk Jang, Hee Jung Cho, Myung Chul Hyun, Sang Bum Lee, Young Keun Cho, Chang Ho Han
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Clin Exp Pediatr. 2000;43(2):203-209. Published online February 15, 2000
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Purpose : To find out the efficacy, safety and early complication of radiofrequency catheter ablation(RFCA) in pediatric patients with paroxysmal tachycardia, we compared short-term results of RFCA in pediatric patients to adult patients.
Methods : We studied 25 patients(11 pediatric patients, 14 adult patients), who underwent RFCA due to paroxysmal supraventricular tachycardia(PSVT) or idiopathic ventricular tachycardia(VT) from November 1997 to August... |
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- Case Report
- Three Cases of Hemolysis After Transcatheter Closure of A Patent Ductus Arteriosus
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Sang-Bum Lee, Myung Chul Hyun
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Clin Exp Pediatr. 2000;43(10):1399-1403. Published online October 15, 2000
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Severe hemolysis occurred after transcatheter occlusion of a patent ductus arteriosus in 3 patients among 41 patients who underwent transcatheter occlusion of a patent ductus arteriosus. The problems were managed by a standard surgical ligation of the duct, leaving the occlusion device(the Rashkind umbrella and a detachable coil) in situ in one patient, surgical removal of the detachable coil and... |
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- Original Article
- Depolarization, Repolarization Inhomogeneity and Late Potential after Surgical Repair of Tetralogy of Fallot
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Soo Young Kim, Myung Chul Hyun, Sang Bum Lee, Seung Tae Kim, Jong Soo Lee
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Clin Exp Pediatr. 1999;42(8):1071-1077. Published online August 15, 1999
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Purpose : After repair of tetralogy of Fallot(TOF), ventricular arrhythmia and sudden death remain as serious late complications which are due to right ventricular systolic and diastolic overloading, exposure to hypoxia and surgical scar. Among the various methods for predicting the risk of such complications, we evaluated signal average ECG(SAECG), QRS duration, QT and JT dispersion, cardiothoracic(CT) ratio, age at... |
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- Assessment of Regional Wall Motion of the Left Ventricle in Children with Congenital Heart Disease
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Chang Hee Han, Jun Ho Huh, Un Seok Nho, Byung Ho Choi, Myung Chul Hyun, Sang Bum Lee
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Clin Exp Pediatr. 1999;42(6):807-816. Published online June 15, 1999
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Purpose : To assess wall motion of the left ventricle in the various forms of congenital heart disease and to select appropriate methods by which to gauge left ventricular wall motion.
Methods : We evaluated left ventricular function, including volume, global ejection fraction, and regional wall motion(Centerline method, Local Ejection Fraction, Curved Perimeter method and Radial method). The evaluation was done... |
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- Clinical Observations of Coarctation of the Aorta
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Hui Jung Cho, Chang Ho Ha, Dong Seok Lee, Myung Chul Hyun, Sang Bum Lee
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Clin Exp Pediatr. 1999;42(4):519-525. Published online April 15, 1999
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Purpose : Due to controveries surrounding in the incidence of coarctation of aorta which reports previously stated rare among Orientals, we evaluated clinical characteristics, natural courses of coarctation of aorta and effects of different surgical modalities.
Methods : Medical records of 51 patients with coarctation of aorta, diagnosed by 2-dimensional echocardiography in Kyungpook University Hospital Pediatric Cardiac Laboratory from June 1985... |
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- Fixed Subaortic Stenosis in Children
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Eun Jin Choi, Byung Ho Choi, Myung Chul Hyun, Sang Bum Lee
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Clin Exp Pediatr. 1997;40(4):505-511. Published online April 15, 1997
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Purpose : This study attempted to describe the Doppler and two-dimensional echocardiographic features of fixed subaortic stenosis, the de novo occurrence and progression of this lesion and to review its etiology, treatment and course.
Methods : We studied 17 patients of fixed subaortic stenosis who, between Jan. 1993 and Jan. 1996, ware diagnosed by echocardiographic examination at Kyungpook National University Hospital.... |
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- Clinical Course of Atrioventricular Septal Defect(AVSD) in Down and non Down syndrome
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Un Seok Nho, Myung Chul Hyun, Sang Bum Lee
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Clin Exp Pediatr. 1996;39(9):1288-1294. Published online September 15, 1996
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Purpose : It is well known that 1/3 - 1/2 of Atrioventricular septal defect(AVSD) patients also
have Down syndrome which may influence the clinical course of AVSD. To know the anatomic
type of AVSD and the effect of Down syndrome on the clinical course of AVSD, we studied
37 cases( Down group: 14 cases, non Down group: 23 cases) who were diagnosed and... |
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- Serial Changes of Doppler Echocardiographic Transvalvular Velocity during the Neonatal Period in Full Term Neonates
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Woo Taek Kim, Myung Chul Hyun, Sang Bum Lee
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Clin Exp Pediatr. 1996;39(7):977-986. Published online July 15, 1996
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Purpose : We performed this study to compare serial measurements which relate to both
ventricular functions in full term neonates for the first three weeks after birth.
Methods : Echocardiographic and pulsed Doppler studies were performed for 20 newborns
during the first 36 hours of life, and subsequent serial studies in the second (n=13) and
third(n=12) weeks of life. Evaluation included measurements of both... |
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- Clinical Significance of Simple Ventricular Septal Defect
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Chang Ro Park, Myung Chul Hyun, Sang Bum Lee
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Clin Exp Pediatr. 1996;39(5):652-657. Published online May 15, 1996
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Purpose : To investigate the clinical significance and frequency of simple VSD by
location of the defect and hemodynamic severity.
Methods : We studied 482 cases who were diagnosed as simple VSD at department of Pediatrics, Kyung Pook University Hospital between December 1983 and July 1993. All cases were diagnosed by 2 dimensional echocardiography and cardiac catheterization
was done in 256 cases.
Results :... |
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- Myocardial Functions Estimated by Pulsed Doppler Echocardiography in Patientswith Chronic Renal Failure
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Hyun June Huh, Byung Ho Choi, Myung Chul Hyun, Sang Bum Lee
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Clin Exp Pediatr. 1996;39(12):1712-1728. Published online December 15, 1996
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Purpose : The objectives of this study were to estimate myocardial functions in patients with
chronic renal failure by pulsed Doppler echocardiography, and investigate correlation between
Doppler and disease parameters.
Methods : We studied 13 patients with chronic renal failure whose creatinine clearance rate
less than 25ml/min. Using pulsed Doppler echocardiography with curve following method, we
measured peak velocity, mean velocity, velocity-time integral and peak... |
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- Clinical Course of the Ostium Secundum Atrial Septal Defect(ASD) and Its Rate of Spontaneous Closure
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Dae Yong Kim, Myung Chul Hyun, Sang Bum Lee
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Clin Exp Pediatr. 1996;39(11):1538-1543. Published online November 15, 1996
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Purpose : To know the natural course of the ostium secundum ASD including its rate of
spontaneous closure.
Methods : We studied 259 cases who were diagnosed as ostium secundum ASD by
2D-echocardiography at Department of Pediatrics, Kyungpook National University Hospital
between Jan. 1985 and Dec. 1994. According to the age at diagnosis, we divided them into
two groups, group I (those diagnosed before 1... |
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- Change of Coronary Arterial Distensibility by Intravenous Infusion of Adenosine in Kawasaki Disease Patients Who Had Coronary Artery Aneurysm
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Myung Chul Hyun
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Clin Exp Pediatr. 1995;38(10):1363-1369. Published online October 15, 1995
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Purpose : To investigate the effect of Kawasaki disease on coronary arterial distensibility, we studied 14 patients with Kawasaki disease who had had coronary artery aneurysms(mean of 4.5years have elapsed after onset of Kawasaki disease).
Methods : Using Hewiett Packard-1500 echocardiogram, we measured RR interval, BP(blood pressure), EDD(end diastolic dimension), ESD(end systolic dimension), FS(fractional shortening), LVPWT(left ventricular posterior wall thickness), peak... |
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- Serial M-mode Echocardiographic Assessment of Left Ventricular Function in Kawasaki Disease
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Byung Ho Choi, Jin Kyung Kim, Myung Chul Hyun, Sang Bum Lee
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Clin Exp Pediatr. 1994;37(6):759-766. Published online June 15, 1994
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To investigate the effect of kawasaki disease on left ventricular function, we studied 92 patients with Kawasaki disease at initial visit, after 3 months (78 patients) and after 1 year (9 patients).
Using serial M-mode echocardiogram, we obtained LVD(d) (left ventricular internal dimension at end diastole), LVD(s)(left ventricular internal dimension at end systole), FS(fractional shortening), ET(ejection time), VmCF(mean velocity of circumferential... |
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- Plasma Atrial Natriuretic Peptide Concentrations of the Pulmonary artery, Aorta and Veins in Children with Cardiac Disease
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Kang Il Lee, Nam Geun Heo, Myung Chul Hyun, Sang Bum Lee, Eun Kyoung Yang, Won Jung Lee
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Clin Exp Pediatr. 1994;37(4):481-493. Published online April 15, 1994
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To study the site of release and factors affecting the releases of the atrial natriuretic peptide (ANP) in the pediatric patients, we measured the plasma ANP concentrations in 23 normal healthy children, 19 patients with congestive heart failure and 16 patients with cardiac disease undergoing diagnostic cardiac catheterization.
The following results were obtained.
1) The plasma ANP concentrations of the vein (226.3¡¾74.9... |
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- Serial Doppler Echocardiographic Evaluation of Anthracycline Induced Left Ventricular Dysfunction in Children
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Nam Geun Heo, Myung Chul Hyun, Kun Soo Lee, Sang Bum Lee
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Clin Exp Pediatr. 1993;36(2):214-222. Published online February 15, 1993
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Anthracycline drugs are chemoterapeutic agents highly effective against a wide range of neoplasms. However, its administration may be complicated by cardiotoxic reactions.
There is a continuum of increasing risk with increasing total dose of drug rather than an absolute cutoff point for total dose drug of that should not be exceeded under any circumstances.
At the present time it appears that a... |
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- A Comparison of Reagent Test Strip-photometer and Laboratory Plasma Glucose Values in Newborns
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Jin Kyung Kim, Myung Chul Hyun, Sang Bum Lee, Heng Mi Kim
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Clin Exp Pediatr. 1992;35(8):1501-1058. Published online August 15, 1992
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Although reagent test strip-photometer method is frequently used to estimate plasma glucose values in nurseries, the accuracy in newborns have not been evaluated previously.
In this study values of 44 samples of laboratory glucose were compared with values simultaneously obtained by reagent test strip-photometer.
Laboratory values were determined by glucose oxidase method using veous plasma. Reagent test strip-photometer values were determined... |
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- Primary Hematuria in Children.
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Myung Chul Hyun, Geum Joo Kim, Kuhn Soo Lee, Ja Hoon Koo
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Clin Exp Pediatr. 1986;29(5):498-503. Published online May 31, 1986
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A clinico-pathological observation was done on 23 children with primary hematuria, who had been admitted to the Pediatric ward of KNU Hospital from January 1981 to August 1985. All children were undergone percutaneous renal biopsy. The following resullts were obtained; Sex distribution showed male predominance with male to female ratio of 2.8:1 and 11 〜15 years of age group... |
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- Case Report
- Three Cases of Glanzmann's Thrombasthenia.
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Sung In Baek, Myung Chul Hyun, Haeng Mi Kim, Kun Soo Lee, Doo Hong Ahn, Hyo Jin Chun, Jay Sik Kim
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Clin Exp Pediatr. 1985;28(11):1153-1157. Published online November 30, 1985
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We experienced 3 cases of Glanzmann' s thrombasthenia of 2 year-old boy, 4 year-old boy, and 5 year-old girlt who represented with frequent epistaxis and petechia. The later two of them are brother and sister.Laboratory findings were characterized by normal platelet counts, markedly diminished clot retraction, prolonged bleeding time, positive Rumpel-Leede test, abnormal platelet adhesion to glass, and complete failure... |
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